I know that this is a really old spot and that this post seems like kind of a cop out, but I don't care. I really should have a category for classic spots and damn right this piece deserves it. It's by Wieden + Kennedy for Heineken's Let A Stranger Drive You Home campaign. It features a classic rap track with one of the catchiest hooks in history; people have compared it to that Journey song except the difference is that Journey totally sucks. It's a perfect set up and a punch that delivers like Heineken had to deliver that cabbie actor his paycheck. Its only industry rival was a campaign that told you to stay thirsty.
Another strong and successful spot was the walk-in fridge one with the match shots of women and men freaking out at their respective pleasures. However, this spot just had it all: great acting, photography, direction, music and message. It's a truly persuasive beer commercial. It's a classic.